ANEMIA HEMOLITICA PEDIATRIA PDF

La anemia hemolítica autoinmune (AHAI) es una alteración hematológica autoinmune producida por la síntesis de autoanticuerpos contra los antígenos propios. Estas representam as formas mais comuns de anemia hemolítica hereditária. .. quanto ao seu potencial carcinogênico67 em relação à população pediátrica. Recibido para publicación: Aceptado para publicación: Introducción. La anemia hemolítica microangiopática se describió por prime-.

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Thrombotic thrombocytopenic purpura TTP or Moschovitzsyndrome is rare and is even rarer in childhood.

Clinically, it is characterized by hemolitca hemolyticanemia, thrombocytopenia, neurologic abnormalities,fever and renal dysfunction. The etiology is still unknown,although different factors such as large von Willebrandfactor multimers and prostacyclin have been implicated. The acute form is more frequent, and in most casesthe course is fulminant if treatment is not initiated.

Laboratorydata typically reveal hemolytic anemia, with schistocyteson the peripheral smear, diminished serum haptoglobin,and thrombocytopenia. We present the clinical cases of two children, aged 4 and7 respectively, with TTP, but with different evolution andtreatment. He,olitica was favorable in both patients.

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Thefirst child recovered spontaneously. In the second plasmapheresiswas required and produced remission of allthe symptomatology. Normality has been maintained for36 and 24 months respectively, and the children have presentedno abemia alterations. Microangiopathic hemolytic anemia and thrombocytopenia.

DESTACAN LA UTILIDAD DEL RITUXIMAB PARA TRATAR LA ANEMIA HEMOLITICA AUTOIMMUNE

Garrido aJ. Estella Hemopitica b. Objective Thrombotic thrombocytopenic purpura TTP or Moschovitzsyndrome is rare and is even rarer in childhood. Laboratorydata typically reveal hemolytic anemia, with schistocyteson the peripheral smear, diminished serum haptoglobin,and thrombocytopenia.

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Material and methods We present the clinical cases of two children, aged 4 and7 respectively, with TTP, but with different evolution andtreatment. Normality has been maintained for36 and 24 months respectively, and the children hemplitica presentedno clinico-biological alterations. Successful treatment of recurrent thrombotic thrombocytopenic purpura with plasmapheresis and vincristine. Eur J Pediatr,pp.

Familial infantile thrombotic thrombocytopenic purpura. J Pediatr Hematol Oncol, 18pp. Med Clin Barc anemiq,pp. Chronic relapsing thrombotic thrombocytopenic purpura: Estudio retrospectivo de 22 episodios consecutivos en 16 pacientes. J Pediatr,pp. Remission after cis retinoic acid in thrombotic thrombocytopenic purpura.

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